1-Aminocyclopropane-1-carboxylate synthase
CLASS OF ENZYMES
EC 4.4.1.14; S-adenozil-L-metionin methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming); 1-aminocyclopropane-1-carboxylate synthase
Aminocyclopropane-1-carboxylic acid synthase (ACC synthase, ACS) () is an enzyme that catalyzes the synthesis of 1-Aminocyclopropane-1-carboxylic acid (ACC), a precursor for ethylene, from S-Adenosyl methionine (AdoMet, SAM), an intermediate in the Yang cycle and activated methyl cycle and a useful molecule for methyl transfer. ACC synthase, like other PLP dependent enzymes, catalyzes the reaction through a quinonoid zwitterion intermediate and uses cofactor pyridoxal phosphate (PLP, the active form of vitamin B6) for stabilization.